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Life Sciences

Functional characterization of enhancer evolution in the primate lineage

Genome Biology Background Enhancers play an important role in morphological evolution and speciation by controlling the spatiotemporal expression of genes. Previous efforts to understand the evolution...

InsP3R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by...

Biology Abstract Background Candida albicans (C. albicans) invasion triggers antifungal innate immunity, and the elevation of cytoplasmic Ca2+ levels via the inositol 1,4,5-trisphosphate receptor (InsP3R) plays a...

Methods for enhancing the reproducibility of biomedical research findings using electronic...

BioData Mining   Abstract Background The ability of external investigators to reproduce published scientific findings is critical for the evaluation and validation of biomedical research by the wider...

Readiness for antimicrobial resistance (AMR) surveillance in Pakistan; a model for...

Antimicrobial Resistance & Infection Control: Abstract Background Limited capacity of laboratories for antimicrobial susceptibility testing (AST) presents a critical diagnostic bottleneck in resource limited countries. This paper...

A functional magnetic resonance imaging investigation of visual hallucinations in the...

Behavioral and Brain Functions Hina Abid, Fayyaz Ahmad, Soo Y. Lee, Hyun W. Park, Dongmi Im, Iftikhar Ahmad and Safee U. Chaudhary | ©  The Author(s) 2016 Abstract Purpose Human beings frequently experience fear, phobia, migraine and hallucinations, however, the cerebral mechanisms underpinning these conditions...